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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2c45a56603c0fe6973c33b28ebde512561edc86615984a0421d68acff09dc45' 
  AND token = '9cKnkvrNE0rEo7coal8YxNXC5z+AK6Lrvk0Yf5oreWI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}