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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '140bf3b8034530ece4d73aad2845e4741fa1a4aa341ce0019996e21e824f08fa' 
  AND token = 'RZTkgrXjri8G7OSbRoNrP6dA6K/6xHLpQiZ8tn9wisA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}