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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a284669787c51c383e975a111d09d9fe6b8c84016129f0cce1a1763ad42a1f4' 
  AND token = 'c8WQCDf8M5FTl5uNhRJtbpHdXZOmNhB1inXRjqbBIZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}