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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e54d6cfc921bb9a285ae640befb90928bead8591e7672f242a008f9a15b625f' 
  AND token = 'RRpj+wyQeLeYx3rEbRXW405qeMU0LTZjvKXgXRjMr7s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}