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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32308b2188b9c96bf8e8d8f57b2186ab7a821049e0b9dfac723b699329bc9d52' 
  AND token = 'lseDtfMSSL/CWR9xpjs3Dplihc/lOC3Dy5+W4yFblEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}