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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '643da7183578ea838e8333cd995a69de281756795753c612876cfdd1cf295c2a' 
  AND token = 'oSc2mZM5c9uA6j2MpgGfi4x+7EBUuV4FVYgW90l0C7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}