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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e31157daddd788c6a67fa2609d4a3d31da0c2db78093f2d61b3a387f1066a3c' 
  AND token = 'atrsCd/F5D2i69kbcz6eN1nLseTBQ7nBVkIY6KSLVl8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}