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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b43afb8b7c897d9aa3247210539c32467e6b58039a42c27ed23c847b546771c3' 
  AND token = 'Z+GbcsOy1oPC6bpnPvwgydaokySeepPbyE6d4a3GSQw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}