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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7749a6ab42a860c9a7938b1bf0fc04ec550afbe02a2fbc8067c7f8406e7853ab' 
  AND token = '6+3Fq+GotVFli9y55PBq7IsnCO/FkWAbfozJGAHLU84=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}