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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e80611c816f38e447a7916799d807c1b8c6df1e7c9b0293ee4f11cb1637ff6ea' 
  AND token = 'nPJ/DlGtJVp8jG+oQIk0nSe1Va+om2JbQHM1waDS6Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}