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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e598a21e8f24b11b9d54588d1413c43a6da32a9018cd643d68158f1baf364963' 
  AND token = '1IUi7bwzZ2c2EioyoUf27K+j55emLV0MJczAkKTdNH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}