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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e430a4f475a2db0ff5c5c051ed84d7f815821f9250ed6e6673efeeb6647b7ccf' 
  AND token = 'nz/E3d8sLBqeDSSk68nJT4YtjzmHgidsfxR9dW1ZYS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}