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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f580a71d6d6d36b0562192d3a126e9c2f8c8350451b73a6286d3d64079ebbf31' 
  AND token = 'B9lU0mqBAGbf1V39TuMy9nPdySoAGkHSo/lLXkMXZTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}