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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6cf044a1abed187ad8ec96d3a06abf51e61cceac30a89345ec45931b01adf7c' 
  AND token = 'HB67z5ULiOZPiFeKLcMW+dpk30PKqI5isEukPN25/rs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}