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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb9a87949b580b7faec0b94d84937cbed1b61354853805d82e0196bd0003da58' 
  AND token = 'ZbOXzwVMuTgE5zKBEQyqhaES1hTCLbhEnL0MugNmf1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}