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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe0c2eee798c6a9b40b7949c03cb605fce2b16baff938b932bb91ebf6ffec4a' 
  AND token = 'Rm1+vRPFBrDhPGFnPNUxRCoS1DYJlCXz8Rxu5m2NxFo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}