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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18405d0e0005e7051f3d84dae4561c85525b5c4a4c2756539ca0f9b798cc0edf' 
  AND token = 'msR7X2iNoyVOOYtFtosMbr+J9jmxcQ2iqNWYc7RDrUA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}