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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c808ca18465aee133718b144c418e987754e3f79297dbd68dfd7e7558a5be11' 
  AND token = 'XC5TkNqCAqGrIr0V77M4QcGEJHY++Lxwdtly69/fcqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}