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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '769e00d3540ebcc420c53ce02d3870377f2345a8a7a04cecb8172d4e52851cf4' 
  AND token = 'Ayv05ZrTQbybN1DDdFvJD1k9wRJ4Dy6EQY5DZaPyPD4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}