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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80ac5cb839a8b59b78091f256fb722c7373d8e4d0e93e598d516d547c219982c' 
  AND token = 'CJiHlv0zri/krvbZiOT3teLfxahLgZUdJmbQJ0g+U3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}