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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '366e3864567f9e7a41c25efe16817397e1189afc81ce0fec3bbe66c82444053a' 
  AND token = 'cFE3dERaaAKaIjxOy57HDc94jkXLqYkzunxOXpGvgV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}