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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09afa2fd187de1d978dfcfaa9873cf7272d49d8e4113f8648a09d30db980127a' 
  AND token = 'MFYgU4BorBQ510Ag5I0JrDpV9SXn9KpPHl8NRg44XaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}