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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1a0a8ada275dbb33b16873dcd9270f822a91bca77f77d90e53cad5d3202b1c' 
  AND token = 'ir0xlfdjpxtayj2nCLtxbvHjOg1rgk89jL8CG9vlbbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}