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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb1359217e6a0d1487b43a19f728cde99065f6a2171a6699fb21631eb82e4700' 
  AND token = 'wqOMUaY1a5QSoy6w4ygZwNUQpDUr+NKDJWnM9NFQT7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}