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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c1b761a6b637e2bc219a187d95f4a880917fd0ca7ec8cdf4bccd2784606312c' 
  AND token = 'RkiMMCNlPfLwFBr5xcUVhAgB+TZXskgNZ9w3gRpJ1NQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}