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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8cd160f3e9d1ab7524e8d0428849a54294fb15d02cecc323a82d9fe894e48ad' 
  AND token = 'SucB+MHur3RAV4/rwPAbYNNAZgGdqdVT9Ut52d3sbBo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}