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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16ca2aecb79484046162b82ee9dc7ba1b66c8cb89bd991e4dddb38757d8f717d' 
  AND token = '1Qg6n//XoE53Z3U2xfze2dlRv8rK2c6CrC7WsnKpI/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}