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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6c47387c1e9352b3d236fe04c76733c3467d2db9c86607accf2b460b24f0478f' 
  AND token = '9by3GjD8g7boYtDM6aWaW8OkdOS+3/hRYn2JXHLvB+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}