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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd0f35932a11b0b18f016abcd11555cae97ce5385b462f19c62d0331c8f5facfe' 
  AND token = 'uSFK5tSTbz9xN5/InG5TG8p8uZ3uQsc2hzMtIerOIWA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}