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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e90867492292f1a33627684121ba78bbe03ca1d30107d9dc2b45178b6bb15cb4' 
  AND token = 'C/RtD4cV1yB6gWoaBZAX0/GdcIt3cWDMKFxXAbhkE6w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}