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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ec0a6f49ff1c35ef748eb7bc1a6e533c310d82384affa7e94fe9d5d97b4f4c1' 
  AND token = 'C725eJPrW/8MMrbyCrL+1ZUA6fxuLm+ihEUB7zyP+Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}