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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d0e531421974a4a0edfac56eebe4a6d5379a9e3ef362274d57b9047062de721' 
  AND token = 'c0RHwizVVEr+BQR98GHdVD3oRzI8rq82T9ssq2N9bX8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}