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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '35e2cc44bd98d505ade80a244647e490f3d702e19e3e9948cbee5e7bc69fb072' 
  AND token = '7FAJXpt8Of0DJaoQvC12yPucZjyCuH3p61790krxXeA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}