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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '343c10b3c633066a7ace94d4395fcd2d2e6ce4820231457ad3503ed9a071ebb9' 
  AND token = 'dIYI4A1B/hnUlgrGzUWme+j4vEh55ocnuErACZF87kU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}