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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33c7747a3798cd6113906cd92d59f1716b0deaa3c8fb3dcf8b7ca2602bafbd1e' 
  AND token = 'P1FQEOfxdyJhDsRJcrXJAE6xEUK/gk4MBA4z3gdlp8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}