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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0cdea7d857c7f2df748bb18b149136824425dc7a89028a9ee891a8a26c0ad4c' 
  AND token = 'cLPAHBuGg71aZdwApERXTZlp9WCYKaMDily7Djryyp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}