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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80c4f4e306a60f9dec5651094f033340e284324b550ca90862b6f087fdb6d303' 
  AND token = 'viloQgS+E+N74WBOwcBwiuiFRg8OcrvUqRVS4HXVMOw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}