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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de4dd97403188a8f08e60445ad0ffedd087f4f03527298754d4e17edb8c5f208' 
  AND token = '5TXmbj6k+l4MX/ZFoymbRUlzyhk3q4DJ9/80afRhrLI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}