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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a839bd9c4beaa5eef92a36ab660855ffc8a61f9e65e8e75419543a590d9207c6' 
  AND token = 'ZV3bE7DoiU5MioOtfONbDARsY8t/9Iwu0xpXFyzrDUU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}