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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18d82c1bea3df2fcc124b896b3bc19bd77d6e182428403332b504ceed2c926cb' 
  AND token = 'sD+K+ADmAeJHnoL9AN1THBnXxf3APh6q19v2d2lqt7Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}