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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '106ecca7aeda62d482482173f5df223695d8d63dc5a33de419a1abda592e13c6' 
  AND token = 'mSqLSCVEL7lDv2Gbd9unrGDpttlnany8jNhs6SYYhL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}