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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5afb1f434ff23cfb9599e6662f5b7dceb671cea907409d0fa038e60d339d58c8' 
  AND token = 'RzAZPV9IjxNXUUo5WMm38BI9zCSkcaYYy2q5o6dVRVQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}