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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e5a8f56a4ac9a95981c47f994226430701ee920c0841d6cc30a7d886827ce4' 
  AND token = 'ydU6o9z7HyMnCdxCUHgVpTnRAZUXXw2hQqIDu+bZub0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}