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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e429806aad824b66928c07f43f246048ae4122dd74aaab9b507d8aeb929c6c' 
  AND token = 'deDZyiruT1IMhJlMD/Jnvvk95mpPj/u2vgEr3jizNSY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}