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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce62ba40a69ce7db8340c7f52af09dc29fb9e02a7bb17cec33622297990db3ec' 
  AND token = 'rsCDtpuZh9uGQagDJC9TQJwPjDRp7BRObR7pdXPF7vM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}