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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1e8390d98f9da01d8eec80c53934f06aeb43e230dfec21774bd06e687bcc8f4' 
  AND token = 'bCHx77BvKkA8A8M8za3DjC9/FrQsxa91rQNeNGV5pqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}