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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5e2cdd61d97d957d5015cac6d78d6d4d5d0bfe5092580e65a9ee467fb50dc6f' 
  AND token = 'iCMXJm6xwokG0d1il4iQigq0iH/+UhIryrN1BhY+iQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}