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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b11894ecb982bfb4d7d5b7d374d236cba1ccada3b1604a9c0b47078ef88032f' 
  AND token = 'ZMWi6hGJNA3BKsuHrYWmnaGn1Pc4V4OKzTWk1oUpO/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}