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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53d4990e48eee7f79776cdb401df43f56a92dd59df14e94090f01e0a4692f91a' 
  AND token = 'MiIBdQ2lENxf3XxNvZv6Lt8HtfRJhqrKR0rEtcRREDU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}