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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'babc5b500e83520f736081b1a05eecd030f146f2395cdfd66316e467da53c387' 
  AND token = 'o8sFBYhzt1nwR06esFilQszkahfs0SH167DO60swDmQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}